I Advertise with us I

Your up-to-the-minute guide to what’s happening in Bahrain and Worldwide

Varieties News Kingdom of Bahrain: Scientists Unravel the Genetic Secrets of the Y Chromosome

Scientific Breakthrough: Unlocking the Mysteries of the Y Chromosome

In a significant stride towards comprehending the intricacies of the human genome, scientists have achieved a momentous feat by unraveling the enigmatic Y chromosome genetic sequence, an accomplishment poised to advance research on male infertility.

Presenting a milestone in genomic understanding, researchers revealed the complete sequence of the human Y chromosome, an element primarily carried by males and passed from father to son. It stands as the 24th and final chromosome to be decoded within the human genome’s threadlike structures, known as chromosomes, that transmit genetic information between cells.

In each cell, individuals possess a pair of sex chromosomes. Males carry one Y and one X chromosome, while females have two X chromosomes, with certain exceptions noted.

The Y chromosome plays a pivotal role in essential reproductive functions such as sperm production, or spermatogenesis, and also holds implications for cancer susceptibility and severity. However, due to its intricate structure, deciphering this chromosome has posed a formidable challenge.

Arang Rhie, a staff scientist at the U.S. National Human Genome Research Institute and lead author of the research published in the journal Nature, attributes this breakthrough to advancements in sequencing technologies and computational methods.

University of California, Santa Cruz (UCSC) biomolecular engineering professor Karen Miga, a co-leader of the Telomere-to-Telomere consortium that undertook this research, highlights that this achievement offers a comprehensive insight into over 50% of the chromosome’s previously elusive genetic information, which had been absent from genome maps.

Though the complete X chromosome sequence was unveiled in 2020, the Y chromosome segment had remained riddled with gaps.

Notably, these findings bear particular significance, as the Y chromosome has historically been overlooked in studies of human diseases. Monika Cechova, a UCSC genomicist and study co-author, underscores the complexity of the Y chromosome, being the smallest and fastest-evolving in the human genome, marked by repetitive DNA sequences.

This milestone work has shed light on medically pertinent regions of the Y chromosome, including a DNA stretch housing genes integral to sperm production. Such a comprehensive understanding of these genes presents potential applications in fertility research and related areas.

Cechova suggests that the newfound knowledge could benefit fertility clinics and further investigations into these genes’ activity, aiding in cases like azoospermia (absence of sperm in semen).

In addition to identifying new Y chromosome genes, the researchers unveiled past misinterpretations of some DNA fragments as bacterial in origin.

This accomplishment adds to the ongoing journey of expanding human genetic insights. The human genome’s initial mapping emerged in 2003, followed by the publication of the first complete version, albeit with partial Y chromosome data, last year. Subsequent iterations, enriched by global diversity, have continued to advance our understanding.

Fully sequencing the Y chromosome paves the way for personalized genomics, signifying a recipe for future applications despite current expenses.

Share Article:

Join the family!

Sign up for a Newsletter.

You have been successfully Subscribed! Ops! Something went wrong, please try again.
  • All Post
  • News Koweit
  • All Post
  • News Middle East
Edit Template

About Us

Breaking News Kingdom of Bahrain is your reliable source for current news and insights from Bahrain and the Middle East. Our dedicated team provides accurate coverage and engaging content to keep you informed. Our platform offers a unique opportunity to make your brand visible in Bahrain and across the globe.

Recent Post

  • All Post
  • Arab News
  • Business News
  • Local News
  • News
  • News Europe
  • News Europe Middle East & Africa Emea
  • News Koweit
  • News Middle East
  • News Oman
  • News Saudi Arabia
  • Opportunity Bahrain News
  • Press Release
  • World News
    •   Back
    • To Do in Bahrain
    • Food Bahrain
    • Attractions Bahrain
    • Travel Bahrain
    • Culture Bahrain
    • Sport Bahrain
    • Kids Bahrain
    • Hotel Bahrain
    •   Back
    • Sport News
    • Culture News
    • Society News
    • Varieties News

© 2023 Build by Opportunity-mena.com